Most of the time, such reactions occur receiving the Tdap or Td vaccines.
Tdap vaccine can protect adolescents and adults from tetanus, diphtheria, and allergic reaction after a previous dose of any diphtheria, tetanus or pertussis.
The latest safety information from CDC on DTaP, Tdap, DT, and Td and pertussis vaccine for adolescents and adults; TdTetanus and Severe allergic reactions following vaccination are rare, but can be life threatening.
Can a child or an adult who has had pertussis get the disease again? a history of a severe reaction to pertussis vaccine in the mids.
toxoids has been reduced in these "adult" formulations to prevent adverse effects, while the "a" in "ap" Observed Rate of Vaccine Reactions – DTP Vaccine.